COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

Viruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strains that show attenuated virulence. Such strains may act as vaccines if the attenuated virus can produce immunity without serious disease. This approach is not...

Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly

At age two, children who were born with neurological abnormalities due to congenital Zika Virus (ZIKV) have a range of neurodevelopmental profiles that can be tracked using a routine neurological assessment, according to a new study published this week in...

COVID-19 nasal vaccine candidate effective at preventing disease transmission, study shows

Breathe in, breathe out. That's how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose. And though remarkable progress has been made in developing intramuscular vaccines against SARS-CoV- 2, such as the readily available Pfizer,...

Saliva test for COVID-19 outperforms commercial swab tests, study shows

In the early days of the pandemic, with commercial COVID tests in short supply, Rockefeller's Robert B. Darnell developed an in-house assay to identify positive cases within the Rockefeller community. It turned out to be easier and safer to administer...

DNA researchers develop critical shortcut to detect and identify known and emerging pathogens

Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses. The new algorithm is...

Pilot study of diet/exercise in young adults with intellectual disabilities is promising

Adhering to a diet and exercise program to manage health can be a challenge for anyone. But maintaining a healthy weight may present unique challenges for young adults with inherent barriers such as cognitive impairment. A pilot study at the...

Discovery about cells’ ‘batteries’ boosts battle against many diseases

A top exercise researcher at the University of Virginia School of Medicine has revealed how our bodies ensure the proper functioning of the powerhouses of our cells. The findings could open the door to better treatments for many common diseases,...

Brain molecule helps ‘wake up’ cells that could help tackle MS and similar diseases

An immunological molecule called fractalkine can boost the production of brain cells that produce myelin, a key factor in diseases such as multiple sclerosis, according to recent research from the University of Alberta. Myelin is an insulating layer around nerves...

Caught in a web: Study reveals that immune cells cooperate to trap and kill bacteria

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria. The newly identified antibacterial mechanism, reported Sept. 10 in Science Advances, could inspire novel strategies for combating Staphylococcus aureus (staph) and other extracellular bacterial...

Elevated stress hormones linked to higher risk of high blood pressure and heart events

Adults with normal blood pressure and high levels of stress hormones were more likely to develop high blood pressure and experience cardiovascular events compared to those who had lower stress hormone levels, according to new research published today in Hypertension,...
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