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Hospital and Drugmaker Move to Build Vast Database of New Yorkers’ DNA

The Mount Sinai Health System began an effort this week to build a vast database of patient genetic information that can be studied by researchers — and by a large pharmaceutical company.The goal is to search for treatments for illnesses...

Leon E. Rosenberg, Geneticist Who Wrote of His Depression, Dies at 89

After working for a while as a peddler, Abraham made enough money to open his own general store. He learned English quickly and even perfected a rural Wisconsin accent, which helped him relate to his customers. Celia, a homemaker, maintained...

Viral Infections and Gene Variant Are Linked to Child Hepatitis Cases

A complex combination of factors could be responsible for the pediatric hepatitis cases that have been puzzling doctors in recent months, according to two small, new studies.The studies are based on just a few dozen cases and have not yet...

The Quest by Circadian Medicine to Make the Most of Our Body Clocks

His observations have resonated with circadian scientists struggling to make headway at their own institutions. “John has managed to elevate the discussion or the awareness of the discussion that needed to happen,” says Elizabeth Klerman, a professor of neurology at...

CRISPR, 10 Years On: Learning to Rewrite the Code of Life

Ten years ago this week, Jennifer Doudna and her colleagues published the results of a test-tube experiment on bacterial genes. When the study came out in the journal Science on June 28, 2012, it did not make headline news. In...

What a Gene and Its Risks Could Mean for Kidney Transplants

Transplant specialists, when evaluating kidneys that come from donors, try to work out how likely it is that the kidney will fail after being transplanted into a recipient. Their risk calculations consider factors including the donor’s age, height, weight and...

Targeting the Uneven Burden of Kidney Disease on Black Americans

“I was all for it,” Malcolm said. So was Martin.When they were tested, the brothers learned they had the variants and that the variants, not lupus, most likely were damaging their kidneys. They hardly knew how to react.“I am still...

Sheldon Krimsky, Who Warned of Profit Motive in Science, Dies at 80

Sheldon Krimsky, a leading scholar of environmental ethics who explored issues at the nexus of science, ethics and biotechnology, and who warned of the perils of private companies underwriting and influencing academic research, died on April 23 in Cambridge, Mass....

F.D.A. Warns Patients About Some Prenatal Genetic Tests

The Food and Drug Administration warned expectant parents on Tuesday about the risk of false positive results from a booming line of prenatal blood tests that screen fetuses for rare genetic conditions.The notice followed a New York Times examination in...

Study Raises Questions About Popular Genetic Test for ‘Abnormal’ Embryos

But the new study also shows the limitations of transferring such embryos. A vast majority of the 144 embryos transferred by the group had only one or two chromosomal abnormalities, but the transfers led to 11 miscarriages in addition to...
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